Zambia has implemented multiple public health measures to curb the spread of COVID-19 within its borders:
Wearing a facemask is required in all public spaces, including on public transport.
Maintaining social distancing of 1 meter (3 feet) is required, and individuals are urged to avoid crowded places.
Individuals must wash their hands frequently with soap and water or sanitize them with an alcohol-based hand sanitizer.
Businesses, governmental institutions, and other establishments may require individuals to adhere to additional COVID-19-related measures to enter their premises or access services. Some establishments and services may be subject to reduced operating schedules.

Unvaccinated individuals traveling to Zambia must provide a negative result from a PCR test taken no more than 72 hours before arrival; children under the age of five are exempt from this requirement. Vaccinated travelers must show proof of a completed vaccination scheme. All travelers must complete a Traveler Health Questionnaire before disembarking their incoming flight; the questionnaire is provided on incoming flights and should be handed to authorities upon arrival. Enhanced controls, including random COVID-19 testing, have been implemented at all points of entry.

Additionally, all travelers arriving with a temperature of 38 C (100.4 F) or higher or who exhibit COVID-19 symptoms are subject to COVID-19 testing and must quarantine at home or in a designated government facility at least until the test result is confirmed.

Passengers leaving Zambia are required to use a certified Ministry of Health COVID-19 testing laboratory and present a Ministry of Health-approved negative PCR travel certificate; while authorities may not always ask travelers to present the certificate, individuals must present a valid certificate when requested.

Travelers departing from, arriving in, or transiting the country should validate their PCR test result via the African Union Trusted Travel or Global Haven systems. These services generate a Trusted Travel reference code, which travelers should present to authorities upon their request. Those whose test was performed outside of Zambia are not exempt from this requirement.